Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10937.145 | 0.9842 | 0.9739 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10937.145 | 0.9842 | 0.9739 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10937.145 | 0.9889 | 0.9816 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10937.145 | 0.9889 | 0.9816 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10937.145 | 0.6583 | 0.4156 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10937.145 | 0.6583 | 0.4156 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10937.145 | 0.0156 | -0.9360 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10937.145 | 0.0156 | -0.9360 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10937.145 | 0.0090 | -0.9592 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10937.145 | 0.0090 | -0.9592 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10937.145 | 0.0102 | -0.9550 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10937.145 | 0.0102 | -0.9550 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10937.145 | 0.0064 | -0.9691 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10937.145 | 0.0064 | -0.9691 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14131.189 | 0.9899 | 0.9836 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14131.189 | 0.9899 | 0.9836 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14131.189 | 0.9495 | 0.9174 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14131.189 | 0.9495 | 0.9174 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14131.189 | 1.0086 | 1.0139 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14131.189 | 1.0086 | 1.0139 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14131.189 | 0.9909 | 0.9851 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14131.189 | 0.9909 | 0.9851 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14131.189 | 0.9440 | 0.9083 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14131.189 | 0.9440 | 0.9083 | 1.2288 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14131.189 | 0.0805 | -0.7427 | 1.2288 |