Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10872.145 | 0.0380 | -0.7307 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10872.145 | 0.0362 | -0.7385 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10872.145 | 0.0362 | -0.7385 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10872.145 | 0.0407 | -0.7192 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10872.145 | 0.0407 | -0.7192 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12523.17 | 1.0161 | 1.0359 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12523.17 | 1.0161 | 1.0359 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12523.17 | 0.9840 | 0.9643 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12523.17 | 0.9840 | 0.9643 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12523.17 | 1.0122 | 1.0271 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12523.17 | 1.0122 | 1.0271 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12523.17 | 0.9714 | 0.9365 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12523.17 | 0.9714 | 0.9365 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12523.17 | 0.9938 | 0.9862 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12523.17 | 0.9938 | 0.9862 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12523.17 | 0.2255 | -0.6186 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12523.17 | 0.2255 | -0.6186 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12523.17 | 0.0379 | -0.9475 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12523.17 | 0.0379 | -0.9475 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12523.17 | 0.0436 | -0.9387 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12523.17 | 0.0436 | -0.9387 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12523.17 | 0.0757 | -0.8867 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12523.17 | 0.0757 | -0.8867 | 0.8990 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14245.189 | 0.9049 | 0.8685 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14245.189 | 0.9049 | 0.8685 | 1.4693 |