Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14245.189 | 0.9128 | 0.8796 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14245.189 | 0.9128 | 0.8796 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14245.189 | 0.8919 | 0.8502 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14245.189 | 0.8919 | 0.8502 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14245.189 | 0.9247 | 0.8963 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14245.189 | 0.9247 | 0.8963 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14245.189 | 0.9094 | 0.8749 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14245.189 | 0.9094 | 0.8749 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14245.189 | 0.3465 | -0.0278 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14245.189 | 0.3465 | -0.0278 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14245.189 | 0.1868 | -0.3616 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14245.189 | 0.1868 | -0.3616 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14245.189 | 0.1599 | -0.4258 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14245.189 | 0.1599 | -0.4258 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14245.189 | 0.6927 | 0.5578 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14245.189 | 0.6927 | 0.5578 | 1.4693 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12239.145 | 0.9800 | 0.9812 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12239.145 | 0.9800 | 0.9812 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12239.145 | 0.9625 | 0.9645 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12239.145 | 0.9625 | 0.9645 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12239.145 | 1.0027 | 1.0025 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12239.145 | 1.0027 | 1.0025 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12239.145 | 1.0219 | 1.0204 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12239.145 | 1.0219 | 1.0204 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12239.145 | 0.9628 | 0.9648 | 2.1348 |