Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11936.145 | 0.9605 | 0.9069 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11936.145 | 0.9605 | 0.9069 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11936.145 | 0.9511 | 0.8847 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11936.145 | 0.9511 | 0.8847 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11936.145 | 0.3414 | -0.4393 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11936.145 | 0.3414 | -0.4393 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11936.145 | 0.1787 | -0.7393 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11936.145 | 0.1787 | -0.7393 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11936.145 | 0.1590 | -0.7730 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11936.145 | 0.1590 | -0.7730 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11936.145 | 0.1442 | -0.7977 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11936.145 | 0.1442 | -0.7977 | 0.8451 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10872.145 | 1.0034 | 1.0041 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10872.145 | 1.0034 | 1.0041 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10872.145 | 1.0511 | 1.0621 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10872.145 | 1.0511 | 1.0621 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10872.145 | 0.9754 | 0.9696 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10872.145 | 0.9754 | 0.9696 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10872.145 | 0.9715 | 0.9649 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10872.145 | 0.9715 | 0.9649 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10872.145 | 0.7380 | 0.6600 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10872.145 | 0.7380 | 0.6600 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10872.145 | 0.0659 | -0.6226 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10872.145 | 0.0659 | -0.6226 | 1.6308 | |
| HCC1569 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10872.145 | 0.0380 | -0.7307 | 1.6308 |