Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12305.17 | 0.2450 | 0.2042 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12305.17 | 0.2450 | 0.2042 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12305.17 | 0.0152 | -0.5578 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12305.17 | 0.0152 | -0.5578 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12305.17 | 0.0043 | -0.7191 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12305.17 | 0.0043 | -0.7191 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12305.17 | 0.0120 | -0.5945 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12305.17 | 0.0120 | -0.5945 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12305.17 | 0.0058 | -0.6879 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12305.17 | 0.0058 | -0.6879 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14122.189 | 0.9895 | 0.9930 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14122.189 | 0.9895 | 0.9930 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14122.189 | 1.0791 | 1.0510 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14122.189 | 1.0791 | 1.0510 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14122.189 | 1.0604 | 1.0392 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14122.189 | 1.0604 | 1.0392 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14122.189 | 1.0904 | 1.0581 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14122.189 | 1.0904 | 1.0581 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14122.189 | 0.8301 | 0.8805 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14122.189 | 0.8301 | 0.8805 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 |