Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14239.189 | 0.7009 | 0.2982 | 0.8223 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10693.145 | 1.0081 | 1.0191 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10693.145 | 1.0081 | 1.0191 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10693.145 | 0.9524 | 0.8884 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10693.145 | 0.9524 | 0.8884 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10693.145 | 1.0251 | 1.0591 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10693.145 | 1.0251 | 1.0591 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10693.145 | 0.9709 | 0.9316 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10693.145 | 0.9709 | 0.9316 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10693.145 | 0.9986 | 0.9966 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10693.145 | 0.9986 | 0.9966 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10693.145 | 0.3782 | -0.3636 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10693.145 | 0.3782 | -0.3636 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10693.145 | 0.2021 | -0.6958 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10693.145 | 0.2021 | -0.6958 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10693.145 | 0.1647 | -0.7608 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10693.145 | 0.1647 | -0.7608 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10693.145 | 0.1450 | -0.7942 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10693.145 | 0.1450 | -0.7942 | 0.8492 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11936.145 | 0.9721 | 0.9342 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11936.145 | 0.9721 | 0.9342 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11936.145 | 0.9302 | 0.8359 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11936.145 | 0.9302 | 0.8359 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11936.145 | 0.9661 | 0.9199 | 0.8451 | |
| HCC1428 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11936.145 | 0.9661 | 0.9199 | 0.8451 |