Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12084.145 | 0.2671 | -0.3533 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12084.145 | 0.2671 | -0.3533 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12084.145 | 0.0918 | -0.7407 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12084.145 | 0.0918 | -0.7407 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12084.145 | 0.0981 | -0.7255 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12084.145 | 0.0981 | -0.7255 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12084.145 | 0.0886 | -0.7483 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12084.145 | 0.0886 | -0.7483 | 1.1692 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14239.189 | 0.9622 | 0.9085 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14239.189 | 0.9622 | 0.9085 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14239.189 | 0.8142 | 0.5577 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14239.189 | 0.8142 | 0.5577 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14239.189 | 0.8781 | 0.7075 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14239.189 | 0.8781 | 0.7075 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14239.189 | 0.9840 | 0.9611 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14239.189 | 0.9840 | 0.9611 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14239.189 | 0.9144 | 0.7938 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14239.189 | 0.9144 | 0.7938 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14239.189 | 0.5444 | -0.0454 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14239.189 | 0.5444 | -0.0454 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14239.189 | 0.1613 | -0.7825 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14239.189 | 0.1613 | -0.7825 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14239.189 | 0.1674 | -0.7726 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14239.189 | 0.1674 | -0.7726 | 0.8223 | |
| HCC1395 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14239.189 | 0.7009 | 0.2982 | 0.8223 |