Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11855.145 | 0.9705 | 0.8851 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11855.145 | 0.9173 | 0.6869 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11855.145 | 0.9173 | 0.6869 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11855.145 | 0.9623 | 0.8542 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11855.145 | 0.9623 | 0.8542 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11855.145 | 0.9285 | 0.7276 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11855.145 | 0.9285 | 0.7276 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11855.145 | 0.9543 | 0.8239 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11855.145 | 0.9543 | 0.8239 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11855.145 | 0.6565 | -0.1280 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11855.145 | 0.6565 | -0.1280 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11855.145 | 0.6028 | -0.2629 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11855.145 | 0.6028 | -0.2629 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11855.145 | 0.3433 | -0.7572 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11855.145 | 0.3433 | -0.7572 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11855.145 | 0.3077 | -0.8043 | 0.5070 | |
| BT-483 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11855.145 | 0.3077 | -0.8043 | 0.5070 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12305.17 | 0.9869 | 0.9905 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12305.17 | 0.9869 | 0.9905 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12305.17 | 0.9524 | 0.9651 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12305.17 | 0.9524 | 0.9651 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12305.17 | 1.0125 | 1.0090 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12305.17 | 1.0125 | 1.0090 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12305.17 | 1.0428 | 1.0305 | 2.7728 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12305.17 | 1.0428 | 1.0305 | 2.7728 |