Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14122.189 | 1.0749 | 1.0484 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14122.189 | 1.0749 | 1.0484 | 3.0232 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14152.189 | 1.0113 | 1.0103 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14152.189 | 1.0113 | 1.0103 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14152.189 | 0.9978 | 0.9980 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14152.189 | 0.9978 | 0.9980 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14152.189 | 0.9391 | 0.9436 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14152.189 | 0.9391 | 0.9436 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14152.189 | 0.9629 | 0.9658 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14152.189 | 0.9629 | 0.9658 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14152.189 | 0.7751 | 0.7808 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14152.189 | 0.7751 | 0.7808 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14152.189 | 0.0003 | -0.9537 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14152.189 | 0.0003 | -0.9537 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14152.189 | 0.0025 | -0.8699 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14152.189 | 0.0025 | -0.8699 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14152.189 | 0.0077 | -0.7820 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14152.189 | 0.0077 | -0.7820 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14152.189 | 0.9817 | 0.9833 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14152.189 | 0.9817 | 0.9833 | 2.1948 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14200.189 | 1.0107 | 1.0064 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14200.189 | 1.0107 | 1.0064 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14200.189 | 0.9909 | 0.9944 | 3.2969 | |
| BT-549 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14200.189 | 0.9909 | 0.9944 | 3.2969 |