Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7449.098 | 1.0114 | 1.0122 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7449.098 | 0.9193 | 0.9119 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7449.098 | 0.6324 | 0.5648 | 1.8675 | |
| HCC1569 | HER2amp | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7449.098 | 0.5941 | 0.5134 | 1.8675 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7450.098 | 1.0319 | 1.0285 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7450.098 | 1.0383 | 1.0343 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7450.098 | 1.0326 | 1.0292 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7450.098 | 1.0744 | 1.0659 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7450.098 | 1.0122 | 1.0110 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7450.098 | 0.9835 | 0.9851 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7450.098 | 0.9954 | 0.9958 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7450.098 | 0.9038 | 0.9107 | 2.2139 | |
| HCC1806 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7450.098 | 0.8947 | 0.9020 | 2.2139 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7452.098 | 1.0437 | 1.0516 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7452.098 | 1.0218 | 1.0258 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7452.098 | 1.0199 | 1.0236 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7452.098 | 1.0280 | 1.0332 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7452.098 | 1.0444 | 1.0524 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7452.098 | 0.9858 | 0.9830 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7452.098 | 0.9811 | 0.9774 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7452.098 | 0.9495 | 0.9392 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7452.098 | 0.8775 | 0.8503 | 1.6799 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7453.098 | 1.0299 | 1.0405 | 1.4660 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7453.098 | 1.0500 | 1.0676 | 1.4660 | |
| HCC1937 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7453.098 | 0.9804 | 0.9732 | 1.4660 |