Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10816.144 | 1.0627 | 1.1376 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10816.144 | 1.0416 | 1.0911 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10816.144 | 1.0767 | 1.1682 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10816.144 | 0.2660 | -0.5300 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10816.144 | 0.2744 | -0.5137 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10816.144 | 0.8433 | 0.6600 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12319.168 | 0.9668 | 0.9305 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12319.168 | 1.0459 | 1.0962 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12319.168 | 1.0522 | 1.1094 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12319.168 | 0.9613 | 0.9191 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12319.168 | 0.9150 | 0.8225 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12319.168 | 0.2845 | -0.4629 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12319.168 | 0.1892 | -0.6496 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12319.168 | 0.2304 | -0.5694 | 0.9560 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12319.168 | 0.1889 | -0.6500 | 0.9560 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12580.168 | 0.9766 | 0.9775 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12580.168 | 0.9638 | 0.9651 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12580.168 | 0.9694 | 0.9706 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12580.168 | 0.9523 | 0.9539 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12580.168 | 0.9328 | 0.9347 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12580.168 | 0.9126 | 0.9146 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 8 | uM | 12580.168 | 0.9174 | 0.9195 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 40 | uM | 12580.168 | 0.9705 | 0.9717 | 2.0973 | |
| MB 157 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 200 | uM | 12580.168 | 0.3076 | 0.1400 | 2.0973 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11056.144 | 0.9984 | 0.9989 | 2.8424 |