Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12056.144 | 1.0059 | 1.0122 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12056.144 | 0.8243 | 0.6401 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12056.144 | 0.9241 | 0.8442 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12056.144 | 0.9850 | 0.9693 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12178.144 | 0.8839 | 0.7104 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12178.144 | 0.9020 | 0.7549 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12178.144 | 0.9826 | 0.9561 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12178.144 | 0.9803 | 0.9503 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12178.144 | 0.8863 | 0.7164 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12178.144 | 0.9910 | 0.9773 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12178.144 | 0.7825 | 0.4657 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12178.144 | 1.0258 | 1.0657 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12178.144 | 0.8716 | 0.6802 | 0.7891 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12291.168 | 1.0292 | 1.1333 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12291.168 | 1.0038 | 1.0172 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12291.168 | 1.0078 | 1.0351 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12291.168 | 0.9363 | 0.7260 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12291.168 | 0.8835 | 0.5156 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12291.168 | 0.7407 | 0.0214 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12291.168 | 0.5119 | -0.5535 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12291.168 | 0.6863 | -0.1390 | 0.4466 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12291.168 | 0.5691 | -0.4339 | 0.4466 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10696.144 | 0.9885 | 0.9495 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10696.144 | 0.9245 | 0.6800 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10696.144 | 0.9426 | 0.7542 | 0.4505 |