Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7528.095 | 0.3973 | -0.3227 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7528.095 | 0.0060 | -0.9950 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 9044.095 | 0.9711 | 0.9202 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 9044.095 | 1.0011 | 1.0029 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 9044.095 | 0.6712 | 0.1508 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 9044.095 | 0.3371 | -0.5570 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 9044.095 | 0.2755 | -0.6651 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 9044.095 | 0.2585 | -0.6934 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 9044.095 | 0.3907 | -0.4563 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 9044.095 | 0.3668 | -0.5020 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 9044.095 | 0.0051 | -0.9987 | 0.7214 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10381.095 | 1.0599 | 1.0930 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10381.095 | 1.0364 | 1.0567 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10381.095 | 0.8490 | 0.7597 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10381.095 | 0.5142 | 0.1888 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10381.095 | 0.3216 | -0.1764 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10381.095 | 0.2996 | -0.2208 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10381.095 | 0.3889 | -0.0445 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10381.095 | 0.0769 | -0.7309 | 1.2787 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10381.095 | 0.0055 | -0.9657 | 1.2787 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7530.095 | 0.9957 | 0.9962 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7530.095 | 0.9569 | 0.9615 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7530.095 | 0.8161 | 0.8285 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7530.095 | 0.2944 | 0.1662 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7530.095 | 0.2404 | 0.0665 | 2.2670 |