Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10880.144 | 0.7054 | 0.6567 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10880.144 | 0.8131 | 0.7887 | 1.8532 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10581.144 | 0.9427 | 0.9044 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10581.144 | 0.8756 | 0.7912 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10581.144 | 0.9215 | 0.8687 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10581.144 | 0.9153 | 0.8583 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10581.144 | 0.9696 | 0.9494 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10581.144 | 0.9109 | 0.8509 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10581.144 | 0.2521 | -0.3628 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10581.144 | 0.4590 | 0.0479 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10581.144 | 0.2589 | -0.3485 | 1.2048 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11854.144 | 1.0035 | 1.0053 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11854.144 | 1.0344 | 1.0524 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11854.144 | 1.0129 | 1.0197 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11854.144 | 1.0383 | 1.0582 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11854.144 | 0.9504 | 0.9238 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11854.144 | 0.4371 | 0.0634 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11854.144 | 0.3039 | -0.1941 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11854.144 | 0.3200 | -0.1618 | 1.3102 | |
| BT-20 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 11854.144 | 0.2740 | -0.2555 | 1.3102 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12056.144 | 0.9875 | 0.9743 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12056.144 | 0.9216 | 0.8391 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12056.144 | 1.0072 | 1.0147 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12056.144 | 1.0103 | 1.0212 | 0.9738 | |
| BT-474 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12056.144 | 0.9439 | 0.8848 | 0.9738 |