Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12566.168 | 1.0567 | 1.0783 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12566.168 | 1.0081 | 1.0113 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12566.168 | 1.0231 | 1.0321 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12566.168 | 1.0212 | 1.0294 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12566.168 | 1.0638 | 1.0879 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12566.168 | 0.9868 | 0.9816 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 8 | uM | 12566.168 | 0.9681 | 0.9553 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 40 | uM | 12566.168 | 1.0390 | 1.0539 | 1.4366 | |
| 184B5 | NM | Basal | JNK-IN-5A | JNK | JNK | 200 | uM | 12566.168 | 0.6482 | 0.4789 | 1.4366 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12224.144 | 0.9551 | 0.9120 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12224.144 | 0.9347 | 0.8719 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12224.144 | 0.9673 | 0.9359 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12224.144 | 0.9791 | 0.9591 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12224.144 | 0.9443 | 0.8907 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12224.144 | 0.9523 | 0.9066 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12224.144 | 0.9413 | 0.8849 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12224.144 | 0.9789 | 0.9587 | 1.0210 | |
| 600MPE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12224.144 | 0.9644 | 0.9302 | 1.0210 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10880.144 | 0.9242 | 0.9167 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10880.144 | 0.9619 | 0.9586 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10880.144 | 0.9967 | 0.9964 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10880.144 | 0.9935 | 0.9929 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10880.144 | 0.9060 | 0.8962 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10880.144 | 0.9852 | 0.9840 | 1.8532 | |
| AU565 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10880.144 | 0.0680 | -0.5311 | 1.8532 |