Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7517.095 | 0.8263 | 0.7664 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7517.095 | 0.3901 | 0.0838 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7517.095 | 0.3000 | -0.0864 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7517.095 | 0.3114 | -0.0641 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7517.095 | 0.4832 | 0.2458 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7517.095 | 0.6571 | 0.5217 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7517.095 | 0.0057 | -0.9304 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7518.095 | 1.0048 | 1.0066 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7518.095 | 0.9854 | 0.9798 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7518.095 | 0.5485 | 0.3195 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7518.095 | 0.3027 | -0.1259 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7518.095 | 0.2808 | -0.1701 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7518.095 | 0.3216 | -0.0884 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7518.095 | 0.4949 | 0.2286 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7518.095 | 0.3440 | -0.0448 | 1.4438 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7518.095 | 0.0149 | -0.8913 | 1.4438 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7523.095 | 0.9671 | 0.9200 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7523.095 | 0.9508 | 0.8806 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7523.095 | 0.8786 | 0.7081 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7523.095 | 0.5560 | -0.0221 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7523.095 | 0.4490 | -0.2464 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7523.095 | 0.4351 | -0.2749 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7523.095 | 0.4371 | -0.2709 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7523.095 | 0.4138 | -0.3179 | 0.8203 | |
| MX1 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7523.095 | 0.0059 | -0.9962 | 0.8203 |