Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7526.095 | 1.0035 | 1.0048 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7526.095 | 1.0132 | 1.0179 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7526.095 | 0.9790 | 0.9713 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7526.095 | 0.4424 | 0.1480 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7526.095 | 0.0650 | -0.6889 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7526.095 | 0.0668 | -0.6830 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7526.095 | 0.0730 | -0.6632 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7526.095 | 0.2986 | -0.1214 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7526.095 | 0.0058 | -0.9402 | 1.4693 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7527.095 | 1.0080 | 1.0083 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7527.095 | 0.9411 | 0.9377 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7527.095 | 0.9593 | 0.9571 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7527.095 | 0.6064 | 0.5408 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7527.095 | 0.0939 | -0.4177 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7527.095 | 0.0846 | -0.4486 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7527.095 | 0.0981 | -0.4041 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7527.095 | 0.3003 | 0.0679 | 1.9173 | |
| SK-BR-3 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7527.095 | 0.0045 | -0.8800 | 1.9173 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7528.095 | 1.0943 | 1.2229 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7528.095 | 1.1216 | 1.2883 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7528.095 | 1.0200 | 1.0471 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7528.095 | 0.6487 | 0.2039 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7528.095 | 0.3409 | -0.4340 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7528.095 | 0.2812 | -0.5484 | 0.8526 | |
| SUM1315MO2 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7528.095 | 0.4552 | -0.2054 | 0.8526 |