Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10379.095 | 0.4782 | 0.4571 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10379.095 | 0.1930 | -0.0131 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10379.095 | 0.1477 | -0.1202 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10379.095 | 0.1234 | -0.1854 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10379.095 | 0.1424 | -0.1339 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10379.095 | 0.1872 | -0.0258 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10379.095 | 0.0014 | -0.8805 | 2.3292 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10380.095 | 1.0338 | 1.0457 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10380.095 | 1.0929 | 1.1243 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10380.095 | 0.9091 | 0.8747 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10380.095 | 0.3281 | -0.0615 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10380.095 | 0.1834 | -0.3677 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10380.095 | 0.1483 | -0.4527 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10380.095 | 0.2320 | -0.2584 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10380.095 | 0.0391 | -0.7785 | 1.4726 | |
| LY2 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10380.095 | 0.0054 | -0.9425 | 1.4726 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7482.095 | 1.0278 | 1.0250 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7482.095 | 1.0474 | 1.0424 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7482.095 | 0.8746 | 0.8824 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7482.095 | 0.2491 | 0.0666 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7482.095 | 0.0619 | -0.4317 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7482.095 | 0.0446 | -0.5099 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7482.095 | 0.0494 | -0.4870 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7482.095 | 0.0726 | -0.3894 | 2.2108 | |
| MB 157 | Unknown | Unknown | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7482.095 | 0.0037 | -0.8414 | 2.2108 |