Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0000853	uM	10880.154	0.9830	0.9809	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.000427	uM	10880.154	0.9198	0.9085	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.00213	uM	10880.154	1.0272	1.0302	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0107	uM	10880.154	0.9959	0.9954	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0533	uM	10880.154	0.8763	0.8574	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	0.267	uM	10880.154	0.0862	-0.4932	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	1.33	uM	10880.154	0.0085	-0.8614	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	6.67	uM	10880.154	0.0118	-0.8337	1.7853
AU565	HER2amp	Luminal	LBH589	HDAC	HDAC	33.3	uM	10880.154	0.0132	-0.8232	1.7853
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.0000853	uM	11854.154	0.9721	0.9574	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.000427	uM	11854.154	0.9133	0.8667	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.00213	uM	11854.154	1.0119	1.0182	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.0107	uM	11854.154	1.0015	1.0023	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.0533	uM	11854.154	1.0294	1.0446	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	0.267	uM	11854.154	0.7851	0.6638	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	1.33	uM	11854.154	0.2289	-0.3485	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	6.67	uM	11854.154	0.1542	-0.5176	1.3146
BT-20	TNBC	Basal A	LBH589	HDAC	HDAC	33.3	uM	11854.154	0.1107	-0.6250	1.3146
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0000853	uM	12056.154	0.9892	0.9764	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.000427	uM	12056.154	0.9151	0.8149	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.00213	uM	12056.154	0.9406	0.8702	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0107	uM	12056.154	0.8406	0.6537	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0533	uM	12056.154	0.6498	0.2477	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	0.267	uM	12056.154	0.1473	-0.7542	0.9136
BT-474	HER2amp	Luminal	LBH589	HDAC	HDAC	1.33	uM	12056.154	0.0154	-0.9792	0.9136

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)