Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7512.095 | 0.5324 | -0.0513 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7512.095 | 0.5357 | -0.0444 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7512.095 | 0.5360 | -0.0437 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7512.095 | 0.5580 | 0.0029 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7512.095 | 0.0088 | -0.9926 | 0.8452 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7515.095 | 0.9386 | 0.8727 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7515.095 | 0.7725 | 0.5297 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7515.095 | 0.9874 | 0.9738 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7515.095 | 0.6960 | 0.3726 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7515.095 | 0.4226 | -0.1826 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7515.095 | 0.4168 | -0.1941 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7515.095 | 0.6648 | 0.3087 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7515.095 | 0.7574 | 0.4986 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7515.095 | 0.0122 | -0.9794 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7516.095 | 1.0025 | 1.0038 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7516.095 | 0.9279 | 0.8915 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7516.095 | 1.0512 | 1.0758 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7516.095 | 0.4994 | 0.1923 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7516.095 | 0.3088 | -0.1667 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7516.095 | 0.3601 | -0.0655 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7516.095 | 0.5325 | 0.2507 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7516.095 | 0.7312 | 0.5839 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7516.095 | 0.0061 | -0.9552 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7517.095 | 0.9719 | 0.9633 | 1.5365 | |
| MDA-MB-453 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7517.095 | 1.0090 | 1.0117 | 1.5365 |