Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7508.095 | 0.2929 | -0.6133 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7508.095 | 0.4591 | -0.2943 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7508.095 | 0.0127 | -0.9942 | 0.7473 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7510.094 | 0.8656 | 0.6755 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7510.094 | 0.7399 | 0.3822 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7510.094 | 0.7970 | 0.5139 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7510.094 | 0.7088 | 0.3113 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7510.094 | 0.6150 | 0.1016 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7510.094 | 0.8279 | 0.5863 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7510.094 | 0.5752 | 0.0148 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7510.094 | 0.3240 | -0.4981 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7510.094 | 0.7209 | 0.3386 | 0.8152 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7511.095 | 1.0645 | 1.1111 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7511.095 | 1.0112 | 1.0194 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7511.095 | 0.9695 | 0.9472 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7511.095 | 0.8613 | 0.7577 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7511.095 | 0.9425 | 0.9002 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7511.095 | 0.9686 | 0.9456 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7511.095 | 0.7003 | 0.4698 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7511.095 | 0.6232 | 0.3287 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7511.095 | 0.7184 | 0.5025 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7512.095 | 0.9427 | 0.8651 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7512.095 | 0.8132 | 0.5659 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7512.095 | 0.5747 | 0.0384 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7512.095 | 0.5871 | 0.0650 | 0.8452 |