Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7468.095 | 0.0008 | -0.9857 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7469.095 | 1.0478 | 1.0499 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7469.095 | 1.0290 | 1.0304 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7469.095 | 0.6410 | 0.5815 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7469.095 | 0.1718 | -0.2106 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7469.095 | 0.1082 | -0.3816 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7469.095 | 0.1139 | -0.3646 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7469.095 | 0.1141 | -0.3639 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7469.095 | 0.0891 | -0.4420 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7469.095 | 0.0031 | -0.9048 | 1.8946 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10418.095 | 1.0026 | 1.0045 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10418.095 | 1.0250 | 1.0436 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10418.095 | 0.5823 | 0.2459 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10418.095 | 0.2444 | -0.4173 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10418.095 | 0.2029 | -0.5048 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10418.095 | 0.2157 | -0.4777 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10418.095 | 0.2063 | -0.4976 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10418.095 | 0.1132 | -0.7030 | 1.1425 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10418.095 | 0.0004 | -0.9979 | 1.1425 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7470.095 | 0.8817 | 0.7991 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7470.095 | 0.7720 | 0.6090 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7470.095 | 0.6547 | 0.4007 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7470.095 | 0.5436 | 0.1979 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7470.095 | 0.2693 | -0.3364 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7470.095 | 0.1878 | -0.5099 | 1.1893 |