Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7473.095 | 0.1159 | 0.0070 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7473.095 | 0.0898 | -0.0716 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7473.095 | 0.1945 | 0.1876 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7473.095 | 0.1258 | 0.0337 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7473.095 | 0.0068 | -0.5912 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7474.095 | 1.0950 | 1.0649 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7474.095 | 0.8552 | 0.8929 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7474.095 | 0.5659 | 0.6370 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7474.095 | 0.3245 | 0.3460 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7474.095 | 0.1778 | 0.0892 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7474.095 | 0.1678 | 0.0673 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7474.095 | 0.2175 | 0.1692 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7474.095 | 0.3271 | 0.3498 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7474.095 | 0.0008 | -0.8363 | 2.8423 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7475.095 | 1.1773 | 1.1517 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7475.095 | 1.2273 | 1.1920 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7475.095 | 0.8146 | 0.8246 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7475.095 | 0.6318 | 0.6284 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7475.095 | 0.4122 | 0.3449 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7475.095 | 0.4579 | 0.4097 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7475.095 | 0.5823 | 0.5699 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7475.095 | 0.6644 | 0.6654 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7475.095 | 0.0013 | -0.8990 | 2.2334 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10379.095 | 1.0881 | 1.0739 | 2.3292 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10379.095 | 0.9594 | 0.9648 | 2.3292 |