Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10696.144 | 0.9531 | 0.7977 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10696.144 | 0.9699 | 0.8689 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10696.144 | 0.7364 | 0.0140 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10696.144 | 0.6048 | -0.3449 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10696.144 | 0.5397 | -0.4913 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10696.144 | 0.6090 | -0.3350 | 0.4505 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11855.144 | 0.9705 | 0.9019 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11855.144 | 0.9301 | 0.7712 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11855.144 | 1.0499 | 1.1704 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11855.144 | 1.0058 | 1.0194 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11855.144 | 0.9370 | 0.7932 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11855.144 | 0.8791 | 0.6111 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11855.144 | 0.6507 | -0.0273 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11855.144 | 0.6708 | 0.0234 | 0.5961 | |
| BT-483 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11855.144 | 0.6477 | -0.0349 | 0.5961 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12305.168 | 1.1262 | 1.0973 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12305.168 | 1.1201 | 1.0927 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12305.168 | 1.0867 | 1.0676 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12305.168 | 1.0559 | 1.0440 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12305.168 | 0.8369 | 0.8626 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12305.168 | 0.2982 | 0.2333 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 8 | uM | 12305.168 | 0.1017 | -0.1977 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 40 | uM | 12305.168 | 0.1714 | -0.0115 | 2.5025 | |
| BT-549 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 200 | uM | 12305.168 | 0.1146 | -0.1585 | 2.5025 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12070.144 | 0.9681 | 0.9455 | 1.1742 |