Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7530.095 | 0.1435 | -0.1505 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7530.095 | 0.1922 | -0.0338 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7530.095 | 0.0092 | -0.7477 | 2.2670 | |
| SUM149PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7530.095 | 0.0063 | -0.7859 | 2.2670 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7531.095 | 0.9860 | 0.9920 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7531.095 | 0.9675 | 0.9814 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7531.095 | 0.8614 | 0.9172 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7531.095 | 0.2587 | 0.3636 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7531.095 | 0.1016 | 0.0463 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7531.095 | 0.0952 | 0.0274 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7531.095 | 0.1092 | 0.0681 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7531.095 | 0.0030 | -0.6141 | 3.5302 | |
| SUM159PT | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7531.095 | 0.0005 | -0.7677 | 3.5302 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7532.095 | 1.0310 | 1.0842 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7532.095 | 0.8765 | 0.6743 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7532.095 | 0.6805 | 0.1900 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7532.095 | 0.6955 | 0.2255 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7532.095 | 0.6371 | 0.0888 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7532.095 | 0.6224 | 0.0549 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7532.095 | 0.6065 | 0.0187 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7532.095 | 0.1075 | -0.9013 | 0.7413 | |
| SUM185PE | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7532.095 | 0.0062 | -0.9979 | 0.7413 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7533.095 | 1.0357 | 1.0724 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7533.095 | 1.0622 | 1.1264 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7533.095 | 0.9502 | 0.8990 | 0.9850 |