Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7485.095 | 0.0037 | -0.5677 | 3.6625 | |
| MCF 10A | NM | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7485.095 | 0.0043 | -0.5471 | 3.6625 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7486.095 | 0.9781 | 0.9537 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7486.095 | 1.0169 | 1.0357 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7486.095 | 0.8715 | 0.7291 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7486.095 | 0.6352 | 0.2371 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7486.095 | 0.4979 | -0.0440 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7486.095 | 0.4218 | -0.1979 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7486.095 | 0.4764 | -0.0877 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7486.095 | 0.0005 | -0.9993 | 0.9448 | |
| MCF 10F | NM | - | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7486.095 | 0.0005 | -0.9993 | 0.9448 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7490.095 | 0.9534 | 0.9653 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7490.095 | 0.9330 | 0.9497 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7490.095 | 0.7958 | 0.8392 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7490.095 | 0.4135 | 0.4463 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7490.095 | 0.1969 | 0.1013 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7490.095 | 0.1319 | -0.0492 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7490.095 | 0.1266 | -0.0634 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7490.095 | 0.0074 | -0.6705 | 2.7242 | |
| MCF12A | NM | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7490.095 | 0.0047 | -0.7211 | 2.7242 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7492.095 | 1.3789 | 1.7411 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7492.095 | 1.3746 | 1.7327 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7492.095 | 0.8325 | 0.6708 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7492.095 | 1.0349 | 1.0684 | 1.0194 | |
| MCF7 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7492.095 | 1.4088 | 1.7994 | 1.0194 |