Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12070.144 | 1.0170 | 1.0289 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12070.144 | 1.0381 | 1.0647 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12070.144 | 1.0111 | 1.0189 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12070.144 | 0.9430 | 0.9025 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12070.144 | 1.0335 | 1.0569 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12070.144 | 0.1114 | -0.6914 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12070.144 | 0.7641 | 0.5904 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12070.144 | 0.4220 | -0.0407 | 1.1742 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12112.144 | 0.9872 | 0.9866 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12112.144 | 0.9595 | 0.9573 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12112.144 | 1.0375 | 1.0388 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12112.144 | 0.9808 | 0.9798 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12112.144 | 0.9414 | 0.9379 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12112.144 | 1.0160 | 1.0166 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12112.144 | 0.4943 | 0.3846 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12112.144 | 1.0355 | 1.0367 | 1.9163 | |
| HCC1143 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 12112.144 | 0.4389 | 0.3013 | 1.9163 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10753.144 | 1.0135 | 1.0208 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10753.144 | 0.9262 | 0.8856 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10753.144 | 0.9851 | 0.9770 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10753.144 | 0.9896 | 0.9839 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10753.144 | 1.0095 | 1.0146 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10753.144 | 0.2248 | -0.3650 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10753.144 | 0.0650 | -0.7555 | 1.3008 | |
| HCC1187 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10753.144 | 0.0663 | -0.7518 | 1.3008 |