Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11056.144 | 1.0949 | 1.0648 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11056.144 | 0.9623 | 0.9731 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11056.144 | 1.0803 | 1.0551 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11056.144 | 0.8797 | 0.9118 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11056.144 | 0.8161 | 0.8620 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11056.144 | 0.3805 | 0.4237 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11056.144 | 0.7216 | 0.7831 | 2.8424 | |
| MCF 10A | NM | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 11056.144 | 0.1037 | -0.0990 | 2.8424 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12254.144 | 1.0330 | 1.0348 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12254.144 | 0.9516 | 0.9480 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12254.144 | 1.0319 | 1.0336 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12254.144 | 0.9225 | 0.9162 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12254.144 | 0.9584 | 0.9554 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12254.144 | 1.0409 | 1.0430 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12254.144 | 0.9637 | 0.9611 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12254.144 | 1.0232 | 1.0245 | 1.8842 | |
| MCF 10F | NM | - | JNK-IN-5A | JNK | JNK | 133 | uM | 12254.144 | 0.9055 | 0.8974 | 1.8842 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10817.144 | 1.0177 | 1.0242 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10817.144 | 0.9885 | 0.9842 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10817.144 | 0.9975 | 0.9966 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10817.144 | 1.0174 | 1.0237 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10817.144 | 1.0127 | 1.0172 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10817.144 | 0.9082 | 0.8726 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10817.144 | 0.2455 | -0.2337 | 1.4640 | |
| MCF12A | NM | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10817.144 | 0.2180 | -0.2935 | 1.4640 |