Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10873.144 | 0.9713 | 0.9532 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10873.144 | 0.4321 | 0.0112 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10873.144 | 0.6212 | 0.3583 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10873.144 | 0.5060 | 0.1497 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12400.168 | 1.0284 | 1.0427 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12400.168 | 0.9603 | 0.9398 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12400.168 | 1.0455 | 1.0682 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12400.168 | 1.0283 | 1.0425 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12400.168 | 1.0222 | 1.0333 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12400.168 | 0.9594 | 0.9386 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 8 | uM | 12400.168 | 0.4411 | 0.0796 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 40 | uM | 12400.168 | 0.7813 | 0.6607 | 1.3275 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 200 | uM | 12400.168 | 0.4474 | 0.0912 | 1.3275 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10694.144 | 1.2054 | 1.1803 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10694.144 | 1.1835 | 1.1619 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10694.144 | 1.1236 | 1.1107 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10694.144 | 1.1705 | 1.1509 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10694.144 | 1.1436 | 1.1279 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10694.144 | 0.2528 | 0.0592 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10694.144 | 0.2957 | 0.1389 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10694.144 | 0.2332 | 0.0204 | 2.1636 | |
| Hs 578T | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 10694.144 | 0.1462 | -0.1775 | 2.1636 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10816.144 | 1.0847 | 1.1859 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10816.144 | 1.1642 | 1.3617 | 0.9146 | |
| LY2 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10816.144 | 1.0778 | 1.1708 | 0.9146 |