Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10937.144 | 0.7392 | 0.6451 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10937.144 | 0.6908 | 0.5745 | 1.5466 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10578.144 | 0.9733 | 0.9672 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10578.144 | 0.9087 | 0.8865 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10578.144 | 0.9485 | 0.9365 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10578.144 | 0.9650 | 0.9569 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10578.144 | 0.9767 | 0.9715 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10578.144 | 0.6486 | 0.5353 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10578.144 | 0.2439 | -0.1550 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10578.144 | 0.1794 | -0.2997 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 10578.144 | 0.2128 | -0.2226 | 1.6376 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11850.144 | 0.9674 | 0.9661 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11850.144 | 0.9087 | 0.9036 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11850.144 | 1.0235 | 1.0241 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11850.144 | 1.0521 | 1.0532 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11850.144 | 0.9744 | 0.9735 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11850.144 | 0.5832 | 0.5142 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11850.144 | 0.2998 | 0.0741 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11850.144 | 0.9147 | 0.9100 | 1.9379 | |
| HCC38 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 11850.144 | 0.1009 | -0.3875 | 1.9379 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10873.144 | 1.0268 | 1.0435 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10873.144 | 0.9844 | 0.9745 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10873.144 | 1.0251 | 1.0408 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10873.144 | 1.0693 | 1.1119 | 1.2304 | |
| HCC70 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10873.144 | 1.0144 | 1.0235 | 1.2304 |