Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12192.144 | 0.8883 | 0.6305 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12192.144 | 0.9422 | 0.8048 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12192.144 | 1.0224 | 1.0780 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12192.144 | 1.0742 | 1.2628 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12192.144 | 0.9915 | 0.9708 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12192.144 | 1.0137 | 1.0475 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12192.144 | 0.6011 | -0.1687 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12192.144 | 1.0364 | 1.1272 | 0.5798 | |
| HCC2185 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12192.144 | 0.6252 | -0.1105 | 0.5798 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10577.144 | 1.0217 | 1.0455 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10577.144 | 0.9139 | 0.8197 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10577.144 | 0.9880 | 0.9749 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10577.144 | 1.0187 | 1.0393 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10577.144 | 1.0429 | 1.0902 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10577.144 | 0.9383 | 0.8707 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10577.144 | 0.3559 | -0.3232 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10577.144 | 0.3744 | -0.2864 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10577.144 | 0.3723 | -0.2905 | 0.9534 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10937.144 | 1.0086 | 1.0112 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10937.144 | 0.9854 | 0.9810 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10937.144 | 1.0060 | 1.0078 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10937.144 | 1.0275 | 1.0355 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10937.144 | 0.9546 | 0.9408 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10937.144 | 0.9508 | 0.9358 | 1.5466 | |
| HCC3153 | TNBC | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10937.144 | 0.2833 | -0.1151 | 1.5466 |