Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7449.095 | 0.8964 | 0.8941 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7449.095 | 0.6141 | 0.5695 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7449.095 | 0.5150 | 0.4380 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7449.095 | 0.5415 | 0.4744 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7449.095 | 0.5376 | 0.4691 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7449.095 | 0.3951 | 0.2606 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7449.095 | 0.0016 | -0.9190 | 2.0118 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7450.095 | 1.3097 | 1.3264 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7450.095 | 1.2632 | 1.2798 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7450.095 | 0.9602 | 0.9550 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7450.095 | 0.3924 | 0.1839 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7450.095 | 0.1392 | -0.3375 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7450.095 | 0.1045 | -0.4358 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7450.095 | 0.1263 | -0.3728 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7450.095 | 0.1790 | -0.2374 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7450.095 | 0.0063 | -0.8836 | 1.7844 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7451.095 | 0.9825 | 0.9840 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7451.095 | 0.9706 | 0.9731 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7451.095 | 0.5340 | 0.5043 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7451.095 | 0.2816 | 0.1251 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7451.095 | 0.1280 | -0.2134 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7451.095 | 0.0926 | -0.3210 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7451.095 | 0.0935 | -0.3181 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7451.095 | 0.2159 | -0.0028 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7451.095 | 0.0048 | -0.8230 | 2.2028 |