Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7443.094 | 0.7928 | 0.5385 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7443.094 | 0.6808 | 0.2955 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7443.094 | 0.1424 | -0.7789 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7443.094 | 0.0078 | -0.9917 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7443.094 | 0.0075 | -0.9920 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7444.095 | 0.9528 | 0.8928 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7444.095 | 1.0113 | 1.0257 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7444.095 | 0.8122 | 0.5780 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7444.095 | 0.7022 | 0.3369 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7444.095 | 0.6572 | 0.2397 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7444.095 | 0.5925 | 0.1016 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7444.095 | 0.6038 | 0.1255 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7444.095 | 0.5508 | 0.0136 | 0.8776 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7444.095 | 0.0074 | -0.9926 | 0.8776 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7448.095 | 0.9933 | 0.9954 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7448.095 | 1.0095 | 1.0065 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7448.095 | 0.9855 | 0.9900 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7448.095 | 1.0661 | 1.0445 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7448.095 | 0.9495 | 0.9647 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7448.095 | 0.8868 | 0.9191 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7448.095 | 0.2144 | 0.1783 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7448.095 | 0.0089 | -0.6054 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7448.095 | 0.0075 | -0.6271 | 2.9105 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7449.095 | 0.9979 | 0.9979 | 2.0118 | |
| HCC1569 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7449.095 | 0.9761 | 0.9761 | 2.0118 |