Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7437.095 | 0.8837 | 0.6028 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7437.095 | 0.9134 | 0.7004 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7437.095 | 0.0085 | -0.9996 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7440.095 | 0.9478 | 0.8263 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7440.095 | 0.9211 | 0.7401 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7440.095 | 0.9817 | 0.9384 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7440.095 | 0.8919 | 0.6478 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7440.095 | 0.7816 | 0.3179 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7440.095 | 0.7696 | 0.2837 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7440.095 | 0.7395 | 0.1999 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7440.095 | 0.8597 | 0.5484 | 0.5907 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7440.095 | 0.0902 | -0.9659 | 0.5907 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7442.095 | 1.0058 | 1.0148 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7442.095 | 0.9605 | 0.9000 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7442.095 | 0.8670 | 0.6674 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7442.095 | 0.7603 | 0.4106 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7442.095 | 0.7187 | 0.3130 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7442.095 | 0.6362 | 0.1242 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7442.095 | 0.6328 | 0.1166 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7442.095 | 0.5619 | -0.0402 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7442.095 | 0.0112 | -0.9935 | 0.7851 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7443.094 | 0.9700 | 0.9322 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7443.094 | 1.0128 | 1.0290 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7443.094 | 0.9547 | 0.8979 | 0.8852 | |
| HCC1428 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7443.094 | 0.9102 | 0.7983 | 0.8852 |