Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7433.095 | 0.0037 | -0.9953 | 0.9260 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7435.095 | 1.0266 | 1.0608 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7435.095 | 0.9488 | 0.8836 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7435.095 | 0.9337 | 0.8495 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7435.095 | 0.6193 | 0.1575 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7435.095 | 0.3420 | -0.4121 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7435.095 | 0.3232 | -0.4490 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7435.095 | 0.3584 | -0.3798 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7435.095 | 0.5930 | 0.1017 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7435.095 | 0.1152 | -0.8303 | 0.8762 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7436.095 | 1.0230 | 1.0337 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7436.095 | 1.0016 | 1.0024 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7436.095 | 0.9843 | 0.9768 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7436.095 | 0.7695 | 0.6494 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7436.095 | 0.3263 | -0.1224 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7436.095 | 0.2832 | -0.2092 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7436.095 | 0.3146 | -0.1455 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7436.095 | 0.4843 | 0.1734 | 1.3597 | |
| HCC1395 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7436.095 | 0.0072 | -0.9468 | 1.3597 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7437.095 | 1.0087 | 1.0314 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7437.095 | 1.0017 | 1.0059 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7437.095 | 1.0038 | 1.0136 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7437.095 | 0.9421 | 0.7972 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7437.095 | 0.8853 | 0.6079 | 0.5584 | |
| HCC1419 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7437.095 | 0.8234 | 0.4121 | 0.5584 |