Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7469.098 | 0.9477 | 0.9473 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7469.098 | 0.9427 | 0.9422 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7469.098 | 0.9266 | 0.9256 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7469.098 | 1.0232 | 1.0230 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7469.098 | 0.9936 | 0.9936 | 2.0111 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7470.098 | 0.9870 | 0.9724 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7470.098 | 0.9356 | 0.8630 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7470.098 | 0.8755 | 0.7359 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7470.098 | 0.9506 | 0.8949 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7470.098 | 0.9597 | 0.9142 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7470.098 | 0.9173 | 0.8243 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7470.098 | 0.9556 | 0.9055 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7470.098 | 0.8557 | 0.6940 | 0.9387 | |
| HCC70 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7470.098 | 0.7040 | 0.3761 | 0.9387 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7471.098 | 0.9861 | 0.9877 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7471.098 | 0.9775 | 0.9801 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7471.098 | 0.9421 | 0.9481 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7471.098 | 0.9684 | 0.9719 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7471.098 | 0.9945 | 0.9952 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7471.098 | 0.9433 | 0.9492 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7471.098 | 0.9802 | 0.9825 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7471.098 | 0.9167 | 0.9248 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7471.098 | 0.8611 | 0.8725 | 2.2704 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7472.098 | 1.1957 | 1.2514 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7472.098 | 0.9993 | 0.9991 | 1.5098 |