Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Ispinesib | KSP | Kinesin | 1.33 | uM | 7555.067 | 0.5026 | 0.3308 | 1.6890 | |
| ZR75B | HR+ | Luminal | Ispinesib | KSP | Kinesin | 6.67 | uM | 7555.067 | 0.2659 | -0.0872 | 1.6890 | |
| ZR75B | HR+ | Luminal | Ispinesib | KSP | Kinesin | 33.3 | uM | 7555.067 | 0.0138 | -0.8416 | 1.6890 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5894.095 | 0.9865 | 0.9842 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5894.095 | 0.9954 | 0.9947 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5894.095 | 0.9569 | 0.9492 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5894.095 | 0.9665 | 0.9607 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5894.095 | 0.9377 | 0.9263 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5894.095 | 0.8189 | 0.7799 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5894.095 | 0.0419 | -0.6862 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5894.095 | 0.0058 | -0.9010 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5894.095 | 0.0070 | -0.8892 | 1.7133 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5895.095 | 1.0165 | 1.0225 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5895.095 | 0.9776 | 0.9693 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5895.095 | 0.9009 | 0.8622 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5895.095 | 0.7760 | 0.6817 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5895.095 | 0.6702 | 0.5213 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5895.095 | 0.5976 | 0.4067 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5895.095 | 0.3651 | 0.0044 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5895.095 | 0.0045 | -0.9501 | 1.4629 | |
| 184A1 | NM | Basal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5895.095 | 0.0056 | -0.9421 | 1.4629 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5896.095 | 1.0111 | 1.0143 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5896.095 | 0.9808 | 0.9752 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5896.095 | 0.9205 | 0.8961 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5896.095 | 0.7148 | 0.6111 | 1.5532 |