Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7472.098 | 1.1182 | 1.1536 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7472.098 | 1.0024 | 1.0032 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7472.098 | 1.1964 | 1.2523 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7472.098 | 0.9292 | 0.9050 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7472.098 | 1.1685 | 1.2172 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7472.098 | 1.3134 | 1.3958 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7472.098 | 1.9967 | 2.1618 | 1.5098 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7473.098 | 0.9813 | 0.9835 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7473.098 | 1.1065 | 1.0908 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7473.098 | 0.9694 | 0.9729 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7473.098 | 1.1239 | 1.1051 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7473.098 | 1.0239 | 1.0208 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7473.098 | 0.9372 | 0.9439 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7473.098 | 1.1957 | 1.1630 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7473.098 | 1.2370 | 1.1954 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7473.098 | 2.3320 | 1.8990 | 2.2810 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7474.098 | 1.0433 | 1.0327 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7474.098 | 1.0067 | 1.0051 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7474.098 | 1.1332 | 1.0981 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7474.098 | 1.0712 | 1.0534 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7474.098 | 0.8884 | 0.9113 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7474.098 | 0.9551 | 0.9651 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7474.098 | 1.0062 | 1.0048 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7474.098 | 1.1501 | 1.1101 | 2.6093 | |
| Hs 578T | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7474.098 | 1.0294 | 1.0223 | 2.6093 |