Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7452.095 | 1.0403 | 1.0462 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7452.095 | 0.9969 | 0.9964 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7452.095 | 1.0350 | 1.0402 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7452.095 | 1.0842 | 1.0956 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7452.095 | 1.0728 | 1.0828 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7452.095 | 0.8838 | 0.8623 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7452.095 | 0.0460 | -0.6622 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7452.095 | 0.0104 | -0.8571 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7452.095 | 0.0107 | -0.8545 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7453.095 | 1.0172 | 1.0209 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7453.095 | 1.0003 | 1.0003 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7453.095 | 0.8656 | 0.8314 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7453.095 | 0.6405 | 0.5241 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7453.095 | 0.4930 | 0.2993 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7453.095 | 0.4838 | 0.2844 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7453.095 | 0.5121 | 0.3298 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7453.095 | 0.5248 | 0.3498 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7453.095 | 0.0058 | -0.9133 | 1.6395 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7454.095 | 0.8814 | 0.7896 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7454.095 | 0.8606 | 0.7521 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7454.095 | 0.9170 | 0.8529 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7454.095 | 0.5152 | 0.1151 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7454.095 | 0.0771 | -0.7908 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7454.095 | 0.0731 | -0.8004 | 1.1351 | |
| HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7454.095 | 0.0673 | -0.8145 | 1.1351 |