Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5899.094 | 0.4566 | -0.0635 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 5899.094 | 0.4325 | -0.1112 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5899.094 | 0.5418 | 0.1052 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5899.094 | 0.8551 | 0.7189 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5899.094 | 0.3752 | -0.2255 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 5899.094 | 0.0085 | -0.9801 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 5899.094 | 0.4539 | -0.0687 | 1.0334 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5900.095 | 1.0563 | 1.0507 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5900.095 | 1.0792 | 1.0709 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5900.095 | 0.9885 | 0.9895 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5900.095 | 0.0661 | -0.4220 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5900.095 | 0.0135 | -0.7201 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5900.095 | 0.0209 | -0.6583 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5900.095 | 0.0222 | -0.6490 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5900.095 | 0.0753 | -0.3867 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5900.095 | 0.0005 | -0.9388 | 2.1880 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5901.095 | 0.9190 | 0.9135 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5901.095 | 0.9119 | 0.9057 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5901.095 | 0.5912 | 0.5190 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5901.095 | 0.0250 | -0.7098 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5901.095 | 0.0242 | -0.7149 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5901.095 | 0.0252 | -0.7089 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5901.095 | 0.0276 | -0.6943 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5901.095 | 0.0954 | -0.4154 | 1.9104 | |
| AU565 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5901.095 | 0.0012 | -0.9409 | 1.9104 |