Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5896.095 | 0.6038 | 0.4453 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5896.095 | 0.5118 | 0.2994 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5896.095 | 0.3137 | -0.0518 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5896.095 | 0.0062 | -0.9242 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5896.095 | 0.0056 | -0.9288 | 1.5532 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5897.095 | 1.0253 | 1.0414 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5897.095 | 0.9726 | 0.9550 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5897.095 | 1.0083 | 1.0136 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5897.095 | 0.9143 | 0.8583 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5897.095 | 0.7369 | 0.5572 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5897.095 | 0.6432 | 0.3929 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5897.095 | 0.4421 | 0.0243 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5897.095 | 0.0081 | -0.9614 | 1.2197 | |
| 184B5 | NM | Basal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5897.095 | 0.0068 | -0.9665 | 1.2197 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5898.095 | 0.9955 | 0.9871 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5898.095 | 0.9461 | 0.8472 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5898.095 | 0.9905 | 0.9728 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5898.095 | 0.8590 | 0.6084 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5898.095 | 0.6823 | 0.1561 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5898.095 | 0.6398 | 0.0542 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5898.095 | 0.7167 | 0.2405 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5898.095 | 0.8369 | 0.5493 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5898.095 | 0.0116 | -0.9967 | 0.6975 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5899.094 | 0.9675 | 0.9371 | 1.0334 | |
| 600MPE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 5899.094 | 0.6675 | 0.3526 | 1.0334 |