Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7432.098 | 0.9927 | 0.9860 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7432.098 | 1.0341 | 1.0653 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7432.098 | 1.0847 | 1.1622 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7432.098 | 0.9988 | 0.9976 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7432.098 | 0.9551 | 0.9137 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7432.098 | 0.9662 | 0.9351 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7432.098 | 0.8259 | 0.6647 | 1.0423 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7433.098 | 0.9930 | 0.9877 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7433.098 | 0.9572 | 0.9247 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7433.098 | 1.0119 | 1.0209 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7433.098 | 0.9931 | 0.9878 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7433.098 | 0.9880 | 0.9789 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7433.098 | 0.9691 | 0.9457 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7433.098 | 0.9092 | 0.8397 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7433.098 | 1.0035 | 1.0061 | 1.1392 | |
| HCC1187 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7433.098 | 0.9762 | 0.9581 | 1.1392 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7435.098 | 0.9575 | 0.8902 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7435.098 | 0.9564 | 0.8875 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7435.098 | 0.9587 | 0.8934 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7435.098 | 0.9603 | 0.8975 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7435.098 | 0.9719 | 0.9274 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7435.098 | 0.8942 | 0.7298 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7435.098 | 0.9553 | 0.8848 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7435.098 | 0.9456 | 0.8600 | 0.7702 | |
| HCC1395 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7435.098 | 0.9433 | 0.8541 | 0.7702 |