Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7440.098 | 1.0121 | 1.0676 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7440.098 | 0.9821 | 0.9023 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7440.098 | 0.9789 | 0.8852 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7440.098 | 0.9947 | 0.9707 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7440.098 | 0.9918 | 0.9549 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7440.098 | 0.9531 | 0.7503 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7440.098 | 0.7649 | -0.0490 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7440.098 | 0.6137 | -0.4836 | 0.3606 | |
| HCC1419 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7440.098 | 0.6379 | -0.4251 | 0.3606 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7442.098 | 1.0106 | 1.0246 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7442.098 | 0.9814 | 0.9571 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7442.098 | 1.0315 | 1.0731 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7442.098 | 0.9929 | 0.9835 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7442.098 | 1.0213 | 1.0493 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7442.098 | 0.9794 | 0.9525 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7442.098 | 0.9934 | 0.9847 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7442.098 | 0.9826 | 0.9599 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7442.098 | 1.0011 | 1.0026 | 0.8652 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7443.098 | 0.9855 | 0.9684 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7443.098 | 0.9614 | 0.9160 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7443.098 | 0.9969 | 0.9933 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7443.098 | 0.9920 | 0.9826 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7443.098 | 0.9789 | 0.9540 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7443.098 | 0.9869 | 0.9716 | 0.9189 | |
| HCC1428 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7443.098 | 0.9582 | 0.9092 | 0.9189 |