Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5902.095 | 1.0495 | 1.0965 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5902.095 | 1.0854 | 1.1666 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5902.095 | 0.9660 | 0.9336 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5902.095 | 0.5872 | 0.1894 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5902.095 | 0.2953 | -0.3920 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5902.095 | 0.2691 | -0.4448 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5902.095 | 0.2859 | -0.4109 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5902.095 | 0.2847 | -0.4133 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5902.095 | 0.0087 | -0.9806 | 1.0245 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5904.095 | 1.2103 | 1.6780 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5904.095 | 1.0176 | 1.0540 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5904.095 | 0.5323 | -0.2377 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5904.095 | 0.2849 | -0.7070 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5904.095 | 0.2398 | -0.7749 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5904.095 | 0.2783 | -0.7173 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5904.095 | 0.2631 | -0.7407 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5904.095 | 0.2812 | -0.7129 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5904.095 | 0.0132 | -0.9973 | 0.6537 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10385.095 | 1.0892 | 1.2259 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10385.095 | 1.0369 | 1.0928 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10385.095 | 0.8375 | 0.6016 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10385.095 | 0.4455 | -0.2734 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10385.095 | 0.3174 | -0.5248 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10385.095 | 0.2950 | -0.5665 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10385.095 | 0.3260 | -0.5086 | 0.7986 |