Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10385.095 | 0.4448 | -0.2748 | 0.7986 | |
| BT-20 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10385.095 | 0.0041 | -0.9980 | 0.7986 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5905.095 | 1.0486 | 1.1015 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5905.095 | 0.9887 | 0.9765 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5905.095 | 0.9941 | 0.9878 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5905.095 | 0.6947 | 0.3679 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5905.095 | 0.4747 | -0.0803 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5905.095 | 0.4050 | -0.2206 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5905.095 | 0.5150 | 0.0011 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5905.095 | 0.7166 | 0.4130 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5905.095 | 0.0099 | -0.9837 | 0.9590 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5906.095 | 0.9911 | 0.9737 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5906.095 | 0.9834 | 0.9508 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5906.095 | 0.6381 | 0.0260 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5906.095 | 0.6316 | 0.0106 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5906.095 | 0.4192 | -0.4504 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5906.095 | 0.3834 | -0.5187 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5906.095 | 0.4677 | -0.3533 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5906.095 | 0.7813 | 0.3860 | 0.6731 | |
| BT-474 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5906.095 | 0.0061 | -0.9990 | 0.6731 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5908.095 | 0.9673 | 0.8718 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5908.095 | 0.9143 | 0.6725 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5908.095 | 0.9603 | 0.8445 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5908.095 | 0.8118 | 0.3192 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5908.095 | 0.7959 | 0.2682 | 0.5012 |