Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7454.095 | 0.1315 | -0.6653 | 1.1351 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7454.095 | 0.0092 | -0.9680 | 1.1351 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7455.095 | 1.0292 | 1.0314 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7455.095 | 0.9066 | 0.8966 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7455.095 | 0.5088 | 0.3870 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7455.095 | 0.0950 | -0.4411 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7455.095 | 0.0586 | -0.5700 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7455.095 | 0.0506 | -0.6029 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7455.095 | 0.0536 | -0.5900 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7455.095 | 0.1230 | -0.3573 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7455.095 | 0.0039 | -0.9014 | 1.8461 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7456.095 | 0.9792 | 0.9786 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7456.095 | 0.9627 | 0.9616 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7456.095 | 0.5345 | 0.4526 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7456.095 | 0.0803 | -0.4480 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7456.095 | 0.0273 | -0.6816 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7456.095 | 0.0291 | -0.6712 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7456.095 | 0.0226 | -0.7110 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7456.095 | 0.0867 | -0.4259 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7456.095 | 0.0055 | -0.8594 | 1.9589 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7457.094 | 0.5967 | 0.5121 | 1.8462 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7457.094 | 0.0656 | -0.5427 | 1.8462 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7457.094 | 0.0423 | -0.6394 | 1.8462 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7457.094 | 0.0376 | -0.6616 | 1.8462 | |
HCC1954 | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7457.094 | 0.0417 | -0.6421 | 1.8462 |