Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Ispinesib | KSP | Kinesin | 33.3 | uM | 7458.067 | 0.0041 | -0.9999 | 0.5714 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7462.067 | 1.0506 | 1.2131 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7462.067 | 1.0060 | 1.0246 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7462.067 | 1.0216 | 1.0896 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7462.067 | 0.9952 | 0.9802 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7462.067 | 0.5028 | -0.5122 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.267 | uM | 7462.067 | 0.3521 | -0.7651 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 1.33 | uM | 7462.067 | 0.3681 | -0.7427 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 6.67 | uM | 7462.067 | 0.4490 | -0.6133 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 33.3 | uM | 7462.067 | 0.0065 | -0.9999 | 0.4873 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7463.067 | 0.9994 | 0.9981 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7463.067 | 0.9999 | 0.9997 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7463.067 | 0.9930 | 0.9791 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7463.067 | 0.9388 | 0.8197 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7463.067 | 0.6603 | 0.0753 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.267 | uM | 7463.067 | 0.6721 | 0.1040 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 1.33 | uM | 7463.067 | 0.6187 | -0.0243 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 6.67 | uM | 7463.067 | 0.6823 | 0.1292 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 33.3 | uM | 7463.067 | 0.0003 | -1.0000 | 0.6688 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7464.067 | 1.0229 | 1.0630 | 0.7308 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7464.067 | 1.0530 | 1.1465 | 0.7308 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7464.067 | 1.0129 | 1.0353 | 0.7308 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7464.067 | 1.0373 | 1.1027 | 0.7308 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7464.067 | 0.5392 | -0.1412 | 0.7308 | |
| HCC2185 | TNBC | Luminal | Ispinesib | KSP | Kinesin | 0.267 | uM | 7464.067 | 0.5049 | -0.2150 | 0.7308 |