Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10A	NM	Basal B	L-779450	BRAF	MAPK	1.33	uM	11056.149	0.9145	0.9398	2.9204
MCF 10A	NM	Basal B	L-779450	BRAF	MAPK	6.67	uM	11056.149	0.7305	0.7961	2.9204
MCF 10A	NM	Basal B	L-779450	BRAF	MAPK	33.3	uM	11056.149	0.2227	0.1958	2.9204
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.000128	uM	12254.161	1.0333	1.0474	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.00064	uM	12254.161	0.9973	0.9961	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.0032	uM	12254.161	0.9562	0.9370	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.016	uM	12254.161	0.9905	0.9864	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.08	uM	12254.161	1.0127	1.0182	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	0.4	uM	12254.161	1.0003	1.0004	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	2	uM	12254.161	1.3005	1.4132	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	10	uM	12254.161	0.9061	0.8639	1.3991
MCF 10F	NM	-	L-779450	BRAF	MAPK	50	uM	12254.161	0.1793	-0.4145	1.3991
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.0000853	uM	10817.149	1.0332	1.0451	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.000427	uM	10817.149	0.9740	0.9644	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.00213	uM	10817.149	0.9665	0.9541	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.0107	uM	10817.149	1.0098	1.0133	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.0533	uM	10817.149	1.0045	1.0061	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.267	uM	10817.149	1.0390	1.0529	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	1.33	uM	10817.149	0.9164	0.8843	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	6.67	uM	10817.149	0.6947	0.5598	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	33.3	uM	10817.149	0.3892	0.0505	1.4656
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.0000853	uM	12365.166	1.0483	1.0504	1.8961
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.000427	uM	12365.166	1.0776	1.0804	1.8961
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.00213	uM	12365.166	1.0111	1.0116	1.8961
MCF12A	NM	Basal B	L-779450	BRAF	MAPK	0.0107	uM	12365.166	1.0410	1.0428	1.8961

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)