Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10441.093 | 0.9594 | 0.9289 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10441.093 | 0.9556 | 0.9222 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10441.093 | 0.8552 | 0.7447 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10441.093 | 0.0111 | -0.9605 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10441.093 | 0.0095 | -0.9656 | 1.1458 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10442.093 | 0.9912 | 0.9895 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10442.093 | 0.9595 | 0.9516 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10442.093 | 0.9456 | 0.9347 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10442.093 | 0.9568 | 0.9483 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10442.093 | 0.9876 | 0.9852 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10442.093 | 0.9018 | 0.8810 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10442.093 | 0.7414 | 0.6748 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10442.093 | 0.0067 | -0.8976 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10442.093 | 0.0056 | -0.9075 | 1.6861 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7451.093 | 0.9402 | 0.9445 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7451.093 | 0.9126 | 0.9184 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7451.093 | 0.9856 | 0.9868 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7451.093 | 0.9559 | 0.9593 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7451.093 | 0.9128 | 0.9185 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7451.093 | 0.8322 | 0.8393 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7451.093 | 0.0954 | -0.3149 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7451.093 | 0.0105 | -0.7493 | 2.1935 | |
| HCC1806 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7451.093 | 0.0093 | -0.7628 | 2.1935 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7453.093 | 1.0920 | 1.1141 | 1.5872 | |
| HCC1937 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7453.093 | 1.0607 | 1.0756 | 1.5872 |