Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7436.093 | 0.5092 | 0.1704 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7436.093 | 0.0105 | -0.9463 | 1.2596 | |
| HCC1395 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7436.093 | 0.0076 | -0.9583 | 1.2596 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7437.093 | 1.0357 | 1.1540 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7437.093 | 0.9869 | 0.9450 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7437.093 | 1.0343 | 1.1476 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7437.093 | 1.0404 | 1.1745 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7437.093 | 1.0258 | 1.1108 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7437.093 | 1.0139 | 1.0593 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7437.093 | 0.9608 | 0.8380 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7437.093 | 0.1724 | -0.9513 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7437.093 | 0.0116 | -0.9998 | 0.4731 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7442.1 | 0.9723 | 0.9370 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7442.1 | 0.9470 | 0.8796 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7442.1 | 1.0134 | 1.0306 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7442.1 | 0.9641 | 0.9184 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7442.1 | 0.9514 | 0.8896 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7442.1 | 0.9776 | 0.9491 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7442.1 | 0.8948 | 0.7621 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7442.1 | 0.0366 | -0.9538 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7442.1 | 0.0100 | -0.9894 | 0.8780 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10441.093 | 0.9525 | 0.9169 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10441.093 | 0.9200 | 0.8597 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10441.093 | 0.9766 | 0.9590 | 1.1458 | |
| HCC1428 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10441.093 | 0.9763 | 0.9585 | 1.1458 |